Product ID:CA 15-3 CALIBRATOR B,9C08N
MSDS Date:11/20/1998
FSC:NIIN:Submitter:N EN
Status Code:A
MSDS Number: CKNXG

ABBOTT LABORATORIES

100 ABBOTT PARK RD
ABBOTT PARK, IL 60064-3500
US

Emergency Phone: 847-937-7970

Info Phone: 847-937-3386

Cage: 33110

ABBOTT LABORATORIES INC DIAGNOSTICS DIV

NORTH CHICAGO, IL 60064 US

Telephone: 847-935-7177

Cage: 33110

TRIS(HYDROXYMETHYL)AMINOMETHANE; (TRIS HYDROXYMETHYL

CAS: 77-86-1

RTECS: TY2900000

OSHA PEL N/K

ACGIH TLV: N/K

WATER

CAS: 7732-18-5

RTECS: ZC0110000

OSHA PEL N/K

ACGIH TLV: N/K

SODIUM AZIDE

CAS: 26628-22-8

RTECS: VY8050000

OSHA PEL N/K

ACGIH TLV: N/K

EPA Report Quantity: 1000 LBS

DOT Report Quantity: 1000 LBS

LD50 LC50 Mixture:SEE TOXICOLOGICAL INFORMATION.
Routes of Entry: Inhalation:YES Skin:YES Ingestion:NO
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ROUTES OF EXPOSURE FOR BLOODBORNE
PATHOGENS: NON-INTACT SKIN, MUCOUS MEMBRANES, PARENTERAL CONTACT.
THIS PRODUCT CONTAINS HUMAN SOURCED AND/OR POTENTIALLY INFECTIOUS
COMPONENTS.
Explanation of Carcinogenicity:THIS PRODUCT DOES NOT CONTAIN
CARCINOGENS LISTED BY IARC, NTP, OSHA OR ACGIH.
Effects of Overexposure:SEE HEALTH HAZARDS.
Medical Cond Aggravated by Exposure:PREEXISTING RENAL AILMENTS.

First Aid:INHALATION: REMOVE FROM SOURCE OF EXPOSURE. IF SIGNS OF
TOXICITY OCCUR, SEEK MEDICAL ATTENTION. PROVIDE
SYMPTOMATIC/SUPPORTIVE CARE AS NEEDED. SKIN: REMOVE FROM SOURCE OF
EXPOSURE. WASH AFFECTED AREA WITH SOAP AND WATER. SEEK MEDICAL
ATTENTION AND APPROPRIATE FOLLOW-UP. EYES: FLUSH WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. SEEK MEDICAL ATTENTION
AND APPROPRIATE FOLLOW-UP. INGESTION: R INSE MOUTH WITH WATER. SEEK
MEDICAL ATTENTION AND APPROPRIATE FOLLOW-UP. INFORMATION FOR
DOCTOR: SEE HEALTH HAZARDS SECTION.

Extinguishing Media:CARBON DIOXIDE, EXTINGUISHING POWDER OR WATER
SPRAY. FIGHT LARGER FIRES WITH WATER SPRAY OR ALCOHOL RESISTANT
FOAM.
Fire Fighting Procedures:REPIRATORY PROTECTION NOT NORMALLY REQUIRED
UNLESS EXPOSURE LIMITS FOR COMPONENTS ARE EXCEEDED. WEAR NIOSH
APPROVED SCBA AND FULL PROTECTIVE EQUIPMENT .
Unusual Fire/Explosion Hazard:PRODUCT IS NOT SELFIGNITING. PRODUCT DOES
NOT PRESENT AN EXPLOSION HAZARD.

Spill Release Procedures:NIOSH APPRVD RESP PROT SHOULD BE WORN IF EXPOS
LIMS CAN BE EXCEEDED. HANDLE AS POTENTIALLY INFECTIOUS. PVNT LIQ &
VAP FROM ENTERING INTO SEWAGE SYS, WORKPITS & CELLARS. CONTAIN
SPILL W/APPROP ABSORB M ATL. ABSORB W/LIQ-BINDING MATL (SAND,
DIATOMITE, ACID BINDERS, UNIVERSAL BINDERS, SAWDUST). WEAR PROT
EQUIP. CLEAN AREA W/DETERGENT. APPLY SUITABLE DISINFECTANT. NO
DANGEROUS SUBSTANCES ARE RELEASED.

Handling and Storage Precautions:HANDLE AS A POTENTIALLY INFECTIOUS
MATERIAL. NO SPECIAL MEASURES REQUIRED ABOUT PROTECTION AGAINST
EXPLOSIONS AND FIRES. NO SPECIAL REQUIREMENTS TO BE MET BY
STOREROOMS AND RECEPTACLES. DO NOT STORE T OGETHER WITH ACIDS.
Other Precautions:PROTECT FROM HEAT AND DIRECT SUNLIGHT. STORAGE CLASS:
NOT APPLICABLE. CLASS ACCORDING TO REGULATION ON FLAMMABLE LIQUIDS:
NOT APPLICABLE.

Respiratory Protection:NOT NECESSARY IF ROOM IS WELL-VENTILATED. THE
APPROPRIATE RESPIRATORY PROTECTION SHOULD BE USED IF AIRBORNE
CHEMICAL CONCENTRATION EXCEEDS THE EXPOSURE LIMITS LISTED. WEAR
NIOSH APPROVED RESPIRATOR AP PROPRIATE FOR EXPOSURE OF CONCERN .
Protective Gloves:WEAR WATERPROOF GLOVES IF HAND CONTACT WITH THE
MATERIAL IS ANTICIPATED.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:EYEWASH AND DELUGE SHOWER MEETING ANSI
DESIGN CRITERIA . WEAR LABORATORY COAT OR PROTECTIVE GARB WHEN
WORKING WITH THE MATERIAL.
Work Hygienic Practices:KEEP AWAY FROM FOODSTUFFS, BEVERAGES AND FEED.
WASH HANDS BEFORE BREAKS AND AT THE END OF WORK. THE USUAL
BIOSAFETY PRACTICES FOR HANDLING POTENTIALLY INFECTIOUS MATERIALS
SHOULD BE FOLLOWED.
Supplemental Safety and Health

Boiling Pt:=100.C, 212.F
Melt/Freeze Pt:M.P/F.P Text:NOT DETERMINED
Vapor Pres:23.0 HPA @ 20C
pH:7.4 @ 20C
Solubility in Water:FULLY MISCIBLE
Appearance and Odor:COLORLESS LIQUID; ODORLESS.

Stability Indicator/Materials to Avoid:YES
REACTIONS WITH HEAVY METALS MAY FORM EXPLOSIVE SUBSTANCES. CONTACT WITH
ACIDS MAY RELEASE TOXIC GAS (I.E., HYDROGEN AZIDE HN*3).
Stability Condition to Avoid:NO DECOMPOSITION IF USED ACCORDING TO
SPECIFICATIONS.
Hazardous Decomposition Products:NO DANGEROUS DECOMPOSITION PRODUCTS
KNOWN.

Waste Disposal Methods:RECOMMENDATION: DISPOSE IN ACCORDANCE WITH
FEDERAL, STATE AND LOCAL REGULATIONS. UNCLEANED PACKAGINGS:
RECOMMENDATION: DISPOSE IN ACCORDANCE WITH FEDERAL, STATE AND LOCAL
REGULATIONS. RECOMMENDED CLEA NSING AGENT: WATER, IF NECESSARY WITH
CLEANSING AGENTS.

Toxicological Information:ACUTE TOXICITY: LD/LC50 VALUES FOR HAZARDOUS
INGREDIENTS PER OSHA CRITERIA: COMPONENTS (100% PURE SUBSTANCE/S):
77-86-1 TRIS HYDROXYMETHYL AMINOMETHANE: ORAL: LD50: 590-1780 MG/KG
(RAT); LDLO = 1000 M G/KG IN RABBITS. PRIMARY IRRITANT EFFECTS: ON
THE SKIN: NO IRRITANT EFFECTS; ON THE EYE: NO IRRITANT EFFECTS;
SENSITIZATION: NO SENSITIZING EFFECTS KNOWN; TARGET ORGANS/SYSTEMS:
KIDNEYS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:GENERAL NOTES: DO NOT ALLOW UNDILUTED PRODUCT OR LARGE
QUANTITIES OF IT TO REACH GROUND WATER, WATER COURSES OR SEWAGE
SYSTEM.

Transport Information:DOT REGULATIONS: REMARKS: NOT REGULATED FOR
TRANSPORTATION. LAND TRANSPORT ADR/RID (CROSS-BORDER): REMARKS: NOT
REGULATED FOR TRANSPORTATION; MARINE POLLUTANT: NO; REMARKS: NOT
REGULATED FOR TRANSPORT ATION. ICAO/IATA: REMARKS: NOT REGULATED
FOR TRANSPORTATION.

SARA Title III Information:SARA (SUPERFUND AMENDMENTS AND
REAUTHORIZATION ACT OF 1986 - USA): SECTION 302/304 (40 CFR 355.30
/ 40 CFR 355.40): 26628-22-8 SODIUM AZIDE; SECTION 313 (40 CFR
372.65): 26628-22-8 SODIUM AZIDE.
Federal Regulatory Information:MARKINGS ACCORDING TO EUROPEAN
GUIDELINES: THE PRODUCT HAS BEEN CLASSIFIED & LABELLED IN
ACCORDANCE WITH APPLICABLE EUROPEAN COMMUNITY (EC) DIRECTIVES. CODE
LETTER & HAZARD DESIGNATION OF PRODUCT: XN. HAZARD-DETERMINING
SUBSTANCE/S OF LABELLING: SODIUM AZIDE. RISK PHRASES: 22 HARMFUL IF
SWALLOWED; 32 CONTACT WITH ACIDS LIBERATES VERY TOXIC GAS. SAFETY
PHRASES: 2 KEEP OUT OF THE REACH OF CHILDREN; 13 KEEP AWAY FROM
FOOD, DRINK & ANIMAL FEEDINGSTUFFS; 36 WEAR SUITABLE PROTECTIVE
CLOTHING; 46 IF SW ALLOWED, SEEK MEDICAL ADVICE IMMEDIATELY & SHOW
THIS CONTAINER OR LABEL. CLASSIFICATION/WARNING ACCORDING TO
WORKSAFE AUSTRALIA: HAZARDOUS.
State Regulatory Information:CALIFORNIA PROPOSITION 65 (USA): CHEMICALS
KNOWN TO CAUSE CANCER OR REPRODUCTIVE TOXICITY: THE PRODUCT DOES
NOT CONTAIN LISTED SUBSTANCES.